Buffalo Bills
Record: 7 - 9
2008 Preseason
| Date | Team | Time | Result | Preview | Recap |
| Aug 7 | at Washington | 7:00 pm | - | ||
| Aug 9 | at Washington | 7:00 pm | L 17-14 | Recap | |
| Aug 14 | PITTSBURGH | 7:30 pm | W 24-21 | ||
| Aug 24 | at Indianapolis | 8:00 pm | W 20-7 | Recap | |
| Aug 28 | DETROIT | 6:30 pm | L 14-6 | Recap |
2008 Regular Season
| Date | Team | Time | Result | Preview | Recap |
| Sep 7 | SEATTLE | 1:00 pm | W 34-10 | Preview | Recap |
| Sep 14 | at Jacksonville | 1:00 pm | W 20-16 | Preview | Recap |
| Sep 21 | OAKLAND | 1:00 pm | W 24-23 | Preview | |
| Sep 28 | at St. Louis | 4:05 pm | W 31-14 | Preview | Recap |
| Oct 5 | at Arizona | 4:15 pm | L 41-17 | Preview | Recap |
| Oct 19 | SAN DIEGO | 1:00 pm | W 23-14 | Recap | |
| Oct 26 | at Miami | 1:00 pm | L 25-16 | ||
| Nov 2 | N.Y. Jets | 1:00 pm | L 26-17 | Recap | |
| Nov 9 | at New England | 1:00 pm | L 20-10 | Preview | |
| Nov 17 | CLEVELAND | 8:30 pm | L 29-27 | Preview | Recap |
| Nov 23 | at Kansas City | 1:00 pm | W 54-31 | Recap | |
| Nov 30 | SAN FRANCISCO | 1:00 pm | L 10-3 | Recap | |
| Dec 7 | MIAMI | 4:05 pm | L 16-3 | Preview | |
| Dec 14 | at N.Y. Jets | 1:00 pm | L 31-27 | Preview | Recap |
| Dec 21 | at Denver | 4:05 pm | W 30-23 | Recap | |
| Dec 28 | NEW ENGLAND | 1:00 pm | L 13-0 | Recap |
